exon-research/genomi

An open-source agent harness that turns your AI agent into your personal DNA expert

GitHub repository with 225 stars and 25 forks.

Language: Python

Topics: agent-harness, genome-analysis, whole-genome-sequencing

Open provider repository

24h trend summary

Trending score 1.65, freshness score 0.37, stars gained +1, forks gained +2.

Latest metric snapshot

2026-06-15: 225 stars and 25 forks.

Similar repositories

  1. 1. agentscope-ai/QwenPaw

    Your Personal AI Assistant; easy to install, deploy on your own machine or on the cloud; supports multiple chat apps with easily extensible capabilities.

    GitHub repository with 17,759 stars and 2,614 forks.

    Trending score: 4.09; stars gained: +187; forks gained: +13.

    Language: Python

    Topics: agent, agent-harness, agentscope, harness-engineering, llm-tools, llms

  2. 2. zhnt/loushang

    AI-native agent harness for coding workflows by python: multi-model LLM orchestration, stateful sessions, tool governance, traceable delivery, and provider routing for GPT, Claude, DeepSeek, Qwen, Kimi, GLM, and MiniMax.

    GitHub repository with 187 stars and 45 forks.

    Trending score: 2.76; stars gained: +15; forks gained: +3.

    Language: Python

    Topics: agent, agent-harness, agentic, ai, chatgpt, claude

  3. 3. Picrew/awesome-agent-harness

    An awesome list of Agent Harness engineering resources, including GitHub projects, tools, benchmarks, and practical guides.

    GitHub repository with 1,207 stars and 101 forks.

    Trending score: 2.41; stars gained: +7; forks gained: +3.

    Language: Python

    Topics: agent-harness, context-engineering, harness-engineering

  4. 4. RightNow-AI/AutoMegaKernel

    An agent harness that compiles a model into one provably-correct, self-retargeting CUDA megakernel and self-tunes it past cuBLAS at batch-1 LLM decode.

    GitHub repository with 38 stars and 4 forks.

    Trending score: 1.67; stars gained: +4; forks gained: +0.

    Language: Python

    Topics: agent-harness, cuda, gpu, gpu-programming, kernel-fusion, llm-inference

  5. 5. exon-research/genomi

    An open-source agent harness that turns your AI agent into your personal DNA expert

    GitHub repository with 225 stars and 25 forks.

    Trending score: 1.65; stars gained: +1; forks gained: +2.

    Language: Python

    Topics: agent-harness, genome-analysis, whole-genome-sequencing

  6. 6. mattolson/agent-sandbox

    Secure local dev environment for collaboration with AI coding agents

    GitHub repository with 183 stars and 17 forks.

    Trending score: 1.24; stars gained: +3; forks gained: +1.

    Language: Python

    Topics: agent-sandbox, agents, coding-agents, agent-harness

Trending in Python

  1. 1. chopratejas/headroom

    Compress tool outputs, logs, files, and RAG chunks before they reach the LLM. 60-95% fewer tokens, same answers. Library, proxy, MCP server.

    GitHub repository with 27,902 stars and 1,891 forks.

    Trending score: 6.49; stars gained: +2,776; forks gained: +250.

    Language: Python

    Topics: agent, ai, anthropic, claude-code, compression, context-engineering

  2. 2. harry0703/MoneyPrinterTurbo

    利用AI大模型,一键生成高清短视频 Generate short videos with one click using AI LLM.

    GitHub repository with 88,031 stars and 12,625 forks.

    Trending score: 6.02; stars gained: +1,097; forks gained: +218.

    Language: Python

    Topics: ai, automation, chatgpt, moviepy, python, shortvideo

  3. 3. pewdiepie-archdaemon/odysseus

    Self-hosted AI workspace.

    GitHub repository with 71,346 stars and 9,093 forks.

    Trending score: 5.98; stars gained: +834; forks gained: +140.

    Language: Python

  4. 4. NousResearch/hermes-agent

    The agent that grows with you

    GitHub repository with 193,984 stars and 33,960 forks.

    Trending score: 5.92; stars gained: +753; forks gained: +209.

    Language: Python

    Topics: ai, ai-agent, ai-agents, anthropic, chatgpt, claude

  5. 5. NVIDIA/SkillSpector

    Security scanner for AI agent skills. Detect vulnerabilities, malicious patterns, and security risks.

    GitHub repository with 5,654 stars and 427 forks.

    Trending score: 5.61; stars gained: +874; forks gained: +76.

    Language: Python

  6. 6. rohitg00/ai-engineering-from-scratch

    Learn it. Build it. Ship it for others.

    GitHub repository with 32,527 stars and 5,342 forks.

    Trending score: 5.59; stars gained: +762; forks gained: +135.

    Language: Python

    Topics: agents, ai, ai-agents, ai-engineering, computer-vision, course

Trending topic: agent-harness

  1. 1. agentscope-ai/QwenPaw

    Your Personal AI Assistant; easy to install, deploy on your own machine or on the cloud; supports multiple chat apps with easily extensible capabilities.

    GitHub repository with 17,759 stars and 2,614 forks.

    Trending score: 4.09; stars gained: +187; forks gained: +13.

    Language: Python

    Topics: agent, agent-harness, agentscope, harness-engineering, llm-tools, llms

  2. 2. lobehub/lobehub

    🤯 LobeHub is your Chief Agent Operator, organizing your agents into 7×24 operations by hiring, scheduling, and reporting on your entire AI team.

    GitHub repository with 78,681 stars and 15,427 forks.

    Trending score: 3.82; stars gained: +87; forks gained: +7.

    Language: TypeScript

    Topics: agent, agent-collaboration, agent-harness, ai, cao, chatgpt

  3. 3. zhnt/loushang

    AI-native agent harness for coding workflows by python: multi-model LLM orchestration, stateful sessions, tool governance, traceable delivery, and provider routing for GPT, Claude, DeepSeek, Qwen, Kimi, GLM, and MiniMax.

    GitHub repository with 187 stars and 45 forks.

    Trending score: 2.76; stars gained: +15; forks gained: +3.

    Language: Python

    Topics: agent, agent-harness, agentic, ai, chatgpt, claude

  4. 4. Picrew/awesome-agent-harness

    An awesome list of Agent Harness engineering resources, including GitHub projects, tools, benchmarks, and practical guides.

    GitHub repository with 1,207 stars and 101 forks.

    Trending score: 2.41; stars gained: +7; forks gained: +3.

    Language: Python

    Topics: agent-harness, context-engineering, harness-engineering

  5. 5. thClaws/thClaws

    Open-source AI agent harness in native Rust — GUI, CLI, headless, and webapp from one binary. Multi-provider, MCP, skills, plugins, agent teams.

    GitHub repository with 1,096 stars and 156 forks.

    Trending score: 1.94; stars gained: +10; forks gained: +2.

    Language: Rust

    Topics: agent-harness, ai-agent, multi-provider, rust, tauri, claude-code

  6. 6. RightNow-AI/AutoMegaKernel

    An agent harness that compiles a model into one provably-correct, self-retargeting CUDA megakernel and self-tunes it past cuBLAS at batch-1 LLM decode.

    GitHub repository with 38 stars and 4 forks.

    Trending score: 1.67; stars gained: +4; forks gained: +0.

    Language: Python

    Topics: agent-harness, cuda, gpu, gpu-programming, kernel-fusion, llm-inference